Solid state microwave source development program Final report

Microstrip oscillator for solid state microwave sourc

(Super)twistors and (super)strings

The Lagrangian formulation of the D=4 bosonic string and superstring in terms of the (super)twistors is considered. The (super)twistor form of the equations of motion is derived and the kappa-symmetry transformation for the supertwistors is given. It is shown that the covariant kappa-symmetry gauge fixation results in the action quadratic in the (super)twistor variables.Comment: LaTeX, 17 page

Management considerations of massive hemoptysis while on extracorporeal membrane oxygenation.

BACKGROUND: Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is a life-saving procedure in patients with both respiratory and cardiac failure. Bleeding complications are common since patients must be maintained on anticoagulation. Massive hemoptysis is a rare complication of ECMO; however, it may result in death if not managed thoughtfully and expeditiously. METHODS: A retrospective chart review was performed of consecutive ECMO patients from 7/2010-8/2014 to identify episodes of massive hemoptysis. The management of and the outcomes in these patients were studied. Massive hemoptysis was defined as an inability to control bleeding (\u3e300 mL/day) from the endotracheal tube with conventional maneuvers, such as bronchoscopy with cold saline lavage, diluted epinephrine lavage and selective lung isolation. All of these episodes necessitated disconnecting the ventilator tubing and clamping the endotracheal tube, causing full airway tamponade. RESULTS: During the period of review, we identified 118 patients on ECMO and 3 (2.5%) patients had the complication of massive hemoptysis. One case was directly related to pulmonary catheter migration and the other two were spontaneous bleeding events that were propagated by antiplatelet agents. All three patients underwent bronchial artery embolization in the interventional radiology suite. Anticoagulation was held during the period of massive hemoptysis without any embolic complications. There was no recurrent bleed after appropriate intervention. All three patients were successfully separated from ECMO. CONCLUSIONS: Bleeding complications remain a major issue in patients on ECMO. Disconnection of the ventilator and clamping the endotracheal tube with full respiratory and cardiac support by V-A ECMO is safe. Early involvement of interventional radiology to embolize any potential sources of the bleed can prevent re-hemoptysis and enable continued cardiac and respiratory recovery

Symptom appraisal and help-seeking in men with symptoms of possible prostate cancer: a qualitative study with an ethnically diverse sample in London

This is the final version. Available on open access from the Royal College of General Practitioners via the DOI in this recordBACKGROUND: Prostate cancer mortality in Black males is disproportionately high. This problem may be overcome by reducing delays in the pathway to diagnosis, particularly those occurring before initial medical help seeking. A greater understanding of symptom appraisal and help seeking could support the development of targeted interventions for improving early presentation among Black males. AIM: To provide an in-depth understanding of males' pre-consultation experiences following the onset of symptoms of possible prostate cancer, identifying both general trends as well as potential differences that may exist between Black and White males. DESIGN AND SETTING: Qualitative study of 18 males (nine Black, nine White) in London, UK, who had recently seen their GP with urinary symptoms, erectile dysfunction, or haematuria. METHOD: Semi-structured interviews from a previous multi-methods study of primary care use by males with symptoms of possible prostate cancer were analysed using thematic framework analysis. RESULTS: Symptoms were often interpreted by patients as unimportant. Most delays occurred due to the absence of reasons to seek help, which, in Black males, often stemmed from poor awareness of prostate cancer. This lack of awareness could have been a consequence of their reluctance to seek health information and discuss health issues with others in their social network. Friends and relatives played an important role in symptom appraisal and help seeking. CONCLUSION: Cognitive biases, cultural stigmas, and everyday interpersonal interactions should be important areas at which to target strategies seeking to reduce delays and improve early presentation in males with possible prostate cancer, particularly Black males.Cancer Research UKNational Institute for Health and Care Research (NIHR

Medical Data Architecture Platform and Recommended Requirements for a Medical Data System for Exploration Missions

The Medical Data Architecture (MDA) project supports the Exploration Medical Capability (ExMC) risk to minimize or reduce the risk of adverse health outcomes and decrements in performance due to in-flight medical capabilities on human exploration missions. To mitigate this risk, the ExMC MDA project addresses the technical limitations identified in ExMC Gap Med 07: We do not have the capability to comprehensively process medically- relevant information to support medical operations during exploration missions. This gap identifies that the current in-flight medical data management includes a combination of data collection and distribution methods that are minimally integrated with on-board medical devices and systems. Furthermore, there are a variety of data sources and methods of data collection. For an exploration mission, the seamless management of such data will enable a more medically autonomous crew than the current paradigm of medical data management on the International Space Station. ExMC has recognized that in order to make informed decisions about a medical data architecture framework, current methods for medical data management must not only be understood, but an architecture must also be identified that provides the crew with actionable insight to medical conditions. This medical data architecture will provide the necessary functionality to address the challenges of executing a self-contained medical system that approaches crew health care delivery without assistance from ground support. Hence, the products derived from the third MDA prototype development will directly inform exploration medical system requirements for Level of Care IV in Gateway missions. In fiscal year 2019, the MDA project developed Test Bed 3, the third iteration in a series of prototypes, that featured integrations with cognition tool data, ultrasound image analytics and core Flight Software (cFS). Maintaining a layered architecture design, the framework implemented a plug-in, modular approach in the integration of these external data sources. An early version of MDA Test Bed 3 software was deployed and operated in a simulated analog environment that was part of the Next Space Technologies for Exploration Partnerships (NextSTEP) Gateway tests of multiple habitat prototypes. In addition, the MDA team participated in the Gateway Test and Verification Demonstration, where the MDA cFS applications was integrated with Gateway-in-a-Box software to send and receive medically relevant data over a simulated vehicle network. This software demonstration was given to ExMC and Gateway Program stakeholders at the NASA Johnson Space Center Integrated Power, Avionics and Software (iPAS) facility. Also, the integrated prototypes served as a vehicle to provide Level 5 requirements for the Crew Health and Performance Habitat Data System for Gateway Missions (Medical Level of Care IV). In the upcoming fiscal year, the MDA project will continue to provide systems engineering and vertical prototypes to refine requirements for medical Level of Care IV and inform requirements for Level of Care V

A Note on the Gauge Equivalence between the Manin-Radul and Laberge-Mathieu Super KdV Hierarchies

The gauge equivalence between the Manin-Radul and Laberge-Mathieu super KdV hierarchies is revisited. Apart from the Inami-Kanno transformation, we show that there is another gauge transformation which also possess the canonical property. We explore the relationship of these two gauge transformations from the Kupershmidt-Wilson theorem viewpoint and, as a by-product, obtain the Darboux-Backlund transformation for the Manin-Radul super KdV hierarchy. The geometrical intepretation of these transformations is also briefly discussed.Comment: 8 pages, revtex, 1 figur

Neural superposition and oscillations in the eye of the blowfly

Neural superposition in the eye of the blowfly Calliphora erythrocephala was investigated by stimulating single photoreceptors using corneal neutralization through water immersion. Responses in Large Monopolar Cells (LMCs) in the lamina were measured, while stimulating one or more of the six photoreceptors connected to the LMC. Responses to flashes of low light intensity on individual photoreceptors add approximately linearly at the LMC. Higher intensity light flashes produce a maximum LMC response to illumination of single photoreceptors which is about half the maximum response to simultaneous illumination of the six connecting photoreceptors. This observation indicates that a saturation can occur at a stage of synaptic transmission which precedes the change in the post-synaptic membrane potential. Stimulation of single photoreceptors yields high frequency oscillations (about 200 Hz) in the LMC potential, much larger in amplitude than produced by simultaneous stimulation of the six photoreceptors connected to the LMC. It is discussed that these oscillations also arise from a mechanism that precedes the change in the postsynaptic membrane potential.

Universal Fluctuations of the Danube Water Level: a Link with Turbulence, Criticality and Company Growth

A global quantity, regardless of its precise nature, will often fluctuate according to a Gaussian limit distribution. However, in highly correlated systems, other limit distributions are possible. We have previously calculated one such distribution and have argued that this function should apply specifically, and in many instances, to global quantities that define a steady state. Here we demonstrate, for the first time, the relevance of this prediction to natural phenomena. The river level fluctuations of the Danube are observed to obey our prediction, which immediately establishes a generic statistical connection between turbulence, criticality and company growth statistics.Comment: 5 pages, 1 figur

The Influence of Bars on Nuclear Activity

We test ideas on fueling of galactic nuclei by bar-driven inflow by comparing the detection rate and intensity of nuclear H II regions and AGNs among barred and unbarred galaxies in a sample of over 300 spirals selected from our recent optical spectroscopic survey of nearby galaxies. Among late-type spirals (Sc-Sm), but not early-type (S0/a-Sbc), we observe in the barred group a very marginal increase in the detection rate of H II nuclei and a corresponding decrease in the incidence of AGNs. The minor differences in the detection rates, however, are statistically insignificant, most likely stemming from selection effects and not from a genuine influence from the bar. The presence of a bar seems to have no noticeable impact on the likelihood of a galaxy to host either nuclear star formation or an AGN. The nuclei of early-type barred spirals do exhibit measurably higher star-formation rates than their unbarred counterparts, as indicated by either the luminosity or the equivalent width of H-alpha emission. By contrast, late-type spirals do not show such an effect. Bars have a negligible effect on the strength of the AGNs in our sample, regardless of the Hubble type of the host galaxy. This result confirms similar conclusions reached by other studies based on much smaller samples.Comment: To appear in the Astrophysical Journal. LaTex, 31 pages including 6 postscript figures and 3 tables. AAStex macros include